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Document Type |
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Project |
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Document Title |
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Study the protective role of vitamin C to reduce the harmful impact of exposure to the pesticide and its impact Puff Pugh Alkimouhaoa and histological and behavioral in rats. دراسة الدور الوقائي لفيتامين ج للحد من التأثير الضار عند التعرض للمبيد الحشري بف باف وتأثيره الكيموحيوي والنسيجي والسلوكي في الفئران. |
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Document Language |
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Arabic |
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Abstract |
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I have been through the current study to achieve the objectives of the proposed research plan to study the impact of systems of preventive vitamin C (as one of the drugs poisoning) in reducing the harmful impact in the case of exposure to insecticide Pugh Puff (containing a substance permethrin) through the study of changes in aspects of behavioral and functions of the kidney and liver and heart tissue changes and updated for this. And then were injected with five groups each group of ten mice ages 12 weeks in the peritoneal cavity (ip) of which the first was injected puff Puff only, and the second group were injected Balbv Puff is associated with vitamin C, while the injected third group Balbv Puff then replace the vitamin C, the Group D Vtm injected vitamin C and only represented the group as a fifth officer. Results indicated the animals were subjected to a test tube is narrow that there was no significant difference in the rate of dog bites and the time period of latency. Males also showed a difference morally and alone in a dose of vitamin C in the time period of latency. And motor activity results indicated that there were no significant differences when comparing the group injected with the control group in all behaviors recorded, except the dose of vitamin C with Puff puff showed an increase in the latency time period and then decrease in duration of walking and walking speed. As also shown animals injected dose of vitamin C deficiency in a walk. The animals injected dose led to a different significant difference in the weights of the animals. Puff puff dose caused significant increase in acid urea, as well as significant increase occurred in the vital activities of the enzymes ALK. Got, alk. T,. Albumin, Total protein, Phos. While there has been significant decrease in cardiac enzyme PCK. There was also a significant decrease in Aanzemat. Got, alk. T., ALK. Phos., Albumin, Total, protein Puff puff when you synchronize with vitamin C as well as in the case of replacement of vitamin C Alpav puff shop. The results of microscopic examination to study the pathogenesis of the members of the textile and heart Kabdoualklah degrees. Liver tissue showed moderate pathological changes, while the change did not show any tissue of patients with organic kidney and heart as a result of exposure to the pesticide Puff puff. It is pathological changes caused by swelling of the liver cells and the dark gaps and not to accept the fatty cells of the dye molecules in the chromatin. However, these tissue changes did not appear in the group of mice that coupled with the injected Balbv Puff with vitamin C and through this we can deduce that the replacement property vitamin C to treat cases of poisoning from puff Puff may help to control some of the damage on the basis of the effectiveness of drug at the cellular level and not on the basis of its impact kinetic and level in the body, as was also found that vitamin C helped to hide the toxic Lpf Puff. |
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Publishing Year |
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1420 AH
2000 AD |
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Added Date |
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Wednesday, April 30, 2008 |
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Researchers
| أحمد إبراهيم السقاف | alsaqqaf, ahmed Ibrahim | Investigator | Doctorate | |
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